{"id":86,"date":"2017-11-24T21:39:08","date_gmt":"2017-11-24T21:39:08","guid":{"rendered":"http:\/\/mdxlifesciences.com\/?page_id=86"},"modified":"2018-08-28T01:11:13","modified_gmt":"2018-08-28T01:11:13","slug":"mdx-life-sciences-publications","status":"publish","type":"page","link":"http:\/\/mdxlifesciences.com\/index.php\/mdx-life-sciences-publications\/","title":{"rendered":"MDX LIFESCIENCES Publications"},"content":{"rendered":"

Recent articles\u00a0<\/span><\/h3>\n
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Chance, B., Oshino, N., Sugano, T. and Mayevsky, A. Basic principles of tissue oxygen determination from mitochondrial signals. Adv. Exp. Med. Biol., 37A: 277-292 (1973). (8)<\/a><\/p>\n

Mayevsky, A., and Chance, B. Intracellular oxidation reduction state measured in situ by a multichannel fiber-optic-surface fluorometer. Science 217: 537-540 (1982). (60)<\/a><\/p>\n

Mayevsky, A., Doron, A., Manor, T., Meilin, S., Zarchin, N. and Ouaknine, G.E. Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res. 740: 268-274 (1996). (126)<\/a><\/p>\n

Pevzner, E., Deutsch, A., Manor, T., Dekel, N., Etziony, R., Derzy, I., Razon, N. and Mayevsky, A. Real-time multiparametric spectroscopy as a practical tool for evaluation of tissue vitality in vivo. In: Advances Biomedical and Clinical Diagnostic Systems, Proc. SPIE, vol. 4958, Eds. T. Vo-Dinh, W.S. Grundfest, D.A. Benaron and G.G. Cohn, pp. 171-182 (2003). (170)<\/a><\/p>\n

Mayevsky, A., Manor, T., Pevzner, E., Deutsch, A., Etziony, R., Dekel, N. and Jaronkin, A. Tissue spectroscope: a new in vivo approach to monitor tissue vitality in real time. J. Biomed. Optics 9: 1028-1045 (2004). (178)<\/a><\/p>\n

Deutsch, A., Jaronkin, A., Pevzner, E. and Mayevsky, A. Real time evaluation of tissue vitality by monitoring of microcirculatory blood flow, HbO2 and mitochondrial NADH redox state. In: Optical Fibers and Sensors for Medical Applications IV, Proc. SPIE, vol. 5317, Ed. I. Gannot, pp. 116-127 (2004). (179)<\/a><\/p>\n

Kraut, A., Barbiro-Michaely, E. and Mayevsky, A. Differential effect of norepinephrine on brain and other less vital organs detected by a Multisite Multiparametric Monitoring system. Medical Science Monitor 10: BR215-220 (2004). (181)<\/a><\/p>\n

Mayevsky, A., Deutsch, A., Dekel, N., Pevzner, L. and Jaronkin, A. New biomedical device for in vivo multiparametric evaluation of tissue vitality in critical care medicine. In: Advanced Biomedical and Clinical Diagnosis System III, Proc. SPIE, vol. 5692, Eds. T. Vo-Dinh, W.S. Grundfest, D.A. Benaron and G.E. Cohn, pp. 60-70 (2005). (185)<\/a><\/p>\n

Mayevsky, A. and Rogatsky, G.G. Mitochondrial function in vivo evaluated by NADH fluorescence: From animal models to human studies. Am. J. Physiol. Cell Physiol. 292: C615-C640 (2007). (190)<\/a><\/p>\n

Tolmasov, M., Barbiro-Michaeli, E. and Mayevsky, A. Simultaneously multiparametric spectroscopic monitoring of tissue viability in the brain and small intestine. SPIE Proc. 6434: 1N-1-1N-9 (2007) (194)<\/a><\/p>\n

Meirovitch, E., Sonn, J. and Mayevsky, A. Effect of hyperbaric oxygenation on brain hemodynamics, hemoglobin oxygenation and mitochondrial NADH. Brain Res. Rev. 54: 294-304 (2007). (195)<\/a><\/p>\n

Mayevsky, A. and Chance, B. Oxidation reduction states of NADH in vivo: from animals to clinical use. Mitochondrion 7: 330-339 (2007). (196)<\/a><\/p>\n

Barbiro-Michaely, E., Tolmasov, M., Rinkevich-Shop, S., Sonn, J. and Mayevsky. A. Can the brain sparing effect be detected in small animal model? Med. Sci. Monitor 13: BR211-219 (2007). (197)<\/a><\/p>\n

Mayevsky A., Dekel, N., Oren, L., Deutsch, A. and Pewzner, E. Mitochondrial dysfunction: Bench-to-bedside optical monitoring of tissue vitality. SPIE Proc. 6853: 1B1-1B11 (2008). (199)<\/a><\/p>\n

Clavijo, J.A., Van Bastelaar, J., Pinsky, M.R., Puyana, J.C. and Mayevsky A. A minimally invasive real time monitoring of mitochondrial NADH and tissue blood flow in the urethral wall during hemorrhage and resuscitation. Med. Sci. Monitor 14: BR175-182 (2008). (198)<\/a><\/p>\n

Mayevsky, A. Mitochondrial function and energy metabolism in cancer cells: Past overview and future perspectives. Mitochondrion 9: 165-179 (2009). (213)<\/a><\/p>\n

Mayevsky A., Walden R, Pewzner E, Deutsch A, Heldenberg E, Lavee J , Tager S , Kachel E, Raanani E , Preisman S , Glauber V , Segal E. Mitochondrial function and Tissue Vitality- Bench to Bedside Real Time optical monitoring System. J Biomed Optics 16(6): 067004 1-21 (2011). (228)<\/a><\/p>\n

Mayevsky A. Mitochondrial Function and Tissue Viability In Vivo: From animal experiments to clinical applications. Forty years of fruitful collaboration with Britton Chance. J. Innovative Optical Health Sci. 4: 337-359 (2011). (230)<\/a><\/p>\n

Mayevsky, A. and Barbiro-Michaely E. Shedding light on mitochondrial function by real time monitoring of NADH fluorescence: I. Basic methodology and animal studies. J. Clin. Monit. Comput. 27: 1-34 (2013). (232)<\/a><\/p>\n

Mayevsky, A. and Barbiro-Michaely E. Shedding light on mitochondrial function by real time monitoring of NADH fluorescence: II. Human Studies. J. Clin. Monit. Comput. 27: 125-145 (2013). (233)<\/a><\/p>\n

Mayevsky, A. and Barbiro-Michaely, E. Mitochondrial NADH autofluorescence as a natural biomarker for real-time monitoring of cellular energy metabolism using fluorometers. In: Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications. Editors: V. Ghukasyan and A.A. Heikal. CRC Press, pp, 137-155 (2014). (239)<\/a><\/p>\n

Mayevsky, A. Mitochondrial Function and Metabolic States: On the Differences between Brain In Vitro and In Vivo Conditions and Monitoring. J. of World Mitochondria Society, Issue n\u00b01, Vol. 2 DOI : 10.18143\/JWMS_v2i1.955. (241)<\/a><\/p>\n

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Additional key References<\/span><\/h3>\n
\n

Barbiro E, Zurovsky Y, & Mayevsky A (1998). Real time monitoring of rat liver energy state during ischemia. Microvasc Res 56, 253-260.<\/p>\n

Bolognese P, Miller JI, Heger IM, & Milhorat TH (1993). Laser-Doppler flowmetry in neurosurgery. J Neurosurg Anesthesiol 5, 151-158.<\/p>\n

Chance B, Cohen P, Jobsis F, & Schoener B (1962). Intracellular oxidation-reduction states in vivo. Science 137, 499-508.<\/p>\n

Cordeiro PG, Kirschner RE, Hu Q-Y, Chiao JJC, Savage H, Alfano RR, Hoffman LA, & Hidalgo DA (1995). Ultraviolet excitation fluorescence spectroscopy: A noninvasive method for the measurement of redox changes in ischemic myocutaneous flaps. Plast Reconstr Surg 96, 673-680.<\/p>\n

Coremans JMCC, Ince C, Bruining HA, & Puppels GJ (1997). (Semi-)Quantitive Analysis of reduced Nicotinamide Adenine Dinucleotide Fluorescence images of blood-perfused rat heart. Biophys J 72, 1849-1860.<\/p>\n

Dora E, Gyulai L, & Kovach AGB (1984). Determinants of brain activation-induced cortical NAD\/NADH responses in vivo. Brain Res 299, 61-72.
\nDora E & Kovach AGB (1982). Effect of acute arterial Hypo- and Hypertension on cerebrocortical NAD\/NADH redox state and vascular volume. J CBF Metab 2, 209-219.<\/p>\n

Ince C, Coremans JMCC, & Bruining HA (1992). In vivo NADH fluorescence. In Adv. Exp. Med. :Oxygen Transport to Tissue XIV, eds. Erdmann W & Bruley DF, pp. 277-296. Plenum Press, New York<\/p>\n

Jobsis FF, O\u2019Connor M, Vitale A, & Vreman H (1971). Intracellular redox changes in functioning cerebral cortex. I. Metabolic effects of epileptiform activity. Neurophysiology 3465, 735-749.<\/p>\n

Johansson K (1988). Gastrointestinal application of laser Doppler flowmetry. An experimental and clinical study in cat and man. Acta Chir Scand Suppl 545, 1-64.<\/p>\n

Koretsky AP, Katz LA, & Balaban RS (1987). Determination of pyridine nucleotide fluorescence from the perfused heart using an internal standard. Am J Physiol 253, H856-H862.<\/p>\n

Mayevsky A (1984). Brain NADH redox state monitored in vivo by fiber optic surface fluorometry. Brain Res Rev 7, 49-68.<\/p>\n

Mayevsky A (1993). Biochemical and physiological activities of the brain as in vivo markers of brain pathology. In Cerebral, Revscularization, eds.
\nBernstein EF, Callow AD, Nicolaides AN, & Shifrin EG, pp. 51-69. Med-Orion Pub.<\/p>\n

Mayevsky A & Chance B (1982). Intracellular Oxidation-Reduction State Measured in Situ by a Multicannel Fiber-Optic Surface Fluorometer. Science 217, 537-540.<\/p>\n

Mayevsky A, Doron A, Manor T, Meilin S, Zarchin N, & Ouaknine GE (1996). Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res 740, 268-274.<\/p>\n

Mayevsky A, Meilin S, Manor T, Ornstein E, Zarchin N, & Sonn J (1998). Multiparametric monitoring of brain oxygen balance under experimental and clinical conditions. Neurol Res 20, S76-S80.<\/p>\n

Mayevsky A, Sonn J, Luger-Hamer M, & Nakache R (2003). Real time assessment of organ vitality during the transplantation procedure. Transplantation Revs 17, 96-116.<\/p>\n

Osbakken M & Mayevsky A (1996). Multiparameter monitoring and analysis of in vivo ischemic and hypoxic heart. J Basic Clin Physiol Pharmacol 7, 97-113.<\/p>\n

Rampil IJ, Litt L, & Mayevsky A (1992). Correlated, simultaneous, multiple-wavelength optical monitoring in vivo of localized cerebrocortical NADH and brain microvessel hemoglobin oxygen saturation. J Clin Monit 8, 216-225<\/p>\n

Schabauer AM & Rooke TW (1994). Cutaneous laser Doppler flowmetry: applications and findings. Mayo Clin Proc 69, 564-574.<\/p>\n

Westerman RA, Widdop RE, Hannaford J, Low A, Roberts RG, Kent P, Sideris K, Yip T, Hales JR, & Stephens FR (1988). Laser Doppler velocimetry in the measurement of neurovascular function. Australas Phys Eng Sci Med 11, 53-66.<\/p>\n","protected":false},"excerpt":{"rendered":"

Recent articles\u00a0 Chance, B., Oshino, N., Sugano, T. and Mayevsky, A. Basic principles of tissue oxygen determination from mitochondrial signals. Adv. Exp. Med. Biol., 37A: 277-292 (1973). (8) Mayevsky, A., and Chance, B. Intracellular oxidation reduction state measured in situ by a multichannel fiber-optic-surface fluorometer. Science 217: 537-540 (1982). (60) …<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/pages\/86"}],"collection":[{"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/comments?post=86"}],"version-history":[{"count":14,"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/pages\/86\/revisions"}],"predecessor-version":[{"id":593,"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/pages\/86\/revisions\/593"}],"wp:attachment":[{"href":"http:\/\/mdxlifesciences.com\/index.php\/wp-json\/wp\/v2\/media?parent=86"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}