Recent articles 

Chance, B., Oshino, N., Sugano, T. and Mayevsky, A. Basic principles of tissue oxygen determination from mitochondrial signals. Adv. Exp. Med. Biol., 37A: 277-292 (1973). (8)

Mayevsky, A., and Chance, B. Intracellular oxidation reduction state measured in situ by a multichannel fiber-optic-surface fluorometer. Science 217: 537-540 (1982). (60)

Mayevsky, A., Doron, A., Manor, T., Meilin, S., Zarchin, N. and Ouaknine, G.E. Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res. 740: 268-274 (1996). (126)

Pevzner, E., Deutsch, A., Manor, T., Dekel, N., Etziony, R., Derzy, I., Razon, N. and Mayevsky, A. Real-time multiparametric spectroscopy as a practical tool for evaluation of tissue vitality in vivo. In: Advances Biomedical and Clinical Diagnostic Systems, Proc. SPIE, vol. 4958, Eds. T. Vo-Dinh, W.S. Grundfest, D.A. Benaron and G.G. Cohn, pp. 171-182 (2003). (170)

Mayevsky, A., Manor, T., Pevzner, E., Deutsch, A., Etziony, R., Dekel, N. and Jaronkin, A. Tissue spectroscope: a new in vivo approach to monitor tissue vitality in real time. J. Biomed. Optics 9: 1028-1045 (2004). (178)

Deutsch, A., Jaronkin, A., Pevzner, E. and Mayevsky, A. Real time evaluation of tissue vitality by monitoring of microcirculatory blood flow, HbO2 and mitochondrial NADH redox state. In: Optical Fibers and Sensors for Medical Applications IV, Proc. SPIE, vol. 5317, Ed. I. Gannot, pp. 116-127 (2004). (179)

Kraut, A., Barbiro-Michaely, E. and Mayevsky, A. Differential effect of norepinephrine on brain and other less vital organs detected by a Multisite Multiparametric Monitoring system. Medical Science Monitor 10: BR215-220 (2004). (181)

Mayevsky, A., Deutsch, A., Dekel, N., Pevzner, L. and Jaronkin, A. New biomedical device for in vivo multiparametric evaluation of tissue vitality in critical care medicine. In: Advanced Biomedical and Clinical Diagnosis System III, Proc. SPIE, vol. 5692, Eds. T. Vo-Dinh, W.S. Grundfest, D.A. Benaron and G.E. Cohn, pp. 60-70 (2005). (185)

Mayevsky, A. and Rogatsky, G.G. Mitochondrial function in vivo evaluated by NADH fluorescence: From animal models to human studies. Am. J. Physiol. Cell Physiol. 292: C615-C640 (2007). (190)

Tolmasov, M., Barbiro-Michaeli, E. and Mayevsky, A. Simultaneously multiparametric spectroscopic monitoring of tissue viability in the brain and small intestine. SPIE Proc. 6434: 1N-1-1N-9 (2007) (194)

Meirovitch, E., Sonn, J. and Mayevsky, A. Effect of hyperbaric oxygenation on brain hemodynamics, hemoglobin oxygenation and mitochondrial NADH. Brain Res. Rev. 54: 294-304 (2007). (195)

Mayevsky, A. and Chance, B. Oxidation reduction states of NADH in vivo: from animals to clinical use. Mitochondrion 7: 330-339 (2007). (196)

Barbiro-Michaely, E., Tolmasov, M., Rinkevich-Shop, S., Sonn, J. and Mayevsky. A. Can the brain sparing effect be detected in small animal model? Med. Sci. Monitor 13: BR211-219 (2007). (197)

Mayevsky A., Dekel, N., Oren, L., Deutsch, A. and Pewzner, E. Mitochondrial dysfunction: Bench-to-bedside optical monitoring of tissue vitality. SPIE Proc. 6853: 1B1-1B11 (2008). (199)

Clavijo, J.A., Van Bastelaar, J., Pinsky, M.R., Puyana, J.C. and Mayevsky A. A minimally invasive real time monitoring of mitochondrial NADH and tissue blood flow in the urethral wall during hemorrhage and resuscitation. Med. Sci. Monitor 14: BR175-182 (2008). (198)

Mayevsky, A. Mitochondrial function and energy metabolism in cancer cells: Past overview and future perspectives. Mitochondrion 9: 165-179 (2009). (213)

Mayevsky A., Walden R, Pewzner E, Deutsch A, Heldenberg E, Lavee J , Tager S , Kachel E, Raanani E , Preisman S , Glauber V , Segal E. Mitochondrial function and Tissue Vitality- Bench to Bedside Real Time optical monitoring System. J Biomed Optics 16(6): 067004 1-21 (2011). (228)

Mayevsky A. Mitochondrial Function and Tissue Viability In Vivo: From animal experiments to clinical applications. Forty years of fruitful collaboration with Britton Chance. J. Innovative Optical Health Sci. 4: 337-359 (2011). (230)

Mayevsky, A. and Barbiro-Michaely E. Shedding light on mitochondrial function by real time monitoring of NADH fluorescence: I. Basic methodology and animal studies. J. Clin. Monit. Comput. 27: 1-34 (2013). (232)

Mayevsky, A. and Barbiro-Michaely E. Shedding light on mitochondrial function by real time monitoring of NADH fluorescence: II. Human Studies. J. Clin. Monit. Comput. 27: 125-145 (2013). (233)

Mayevsky, A. and Barbiro-Michaely, E. Mitochondrial NADH autofluorescence as a natural biomarker for real-time monitoring of cellular energy metabolism using fluorometers. In: Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications. Editors: V. Ghukasyan and A.A. Heikal. CRC Press, pp, 137-155 (2014). (239)

Mayevsky, A. Mitochondrial Function and Metabolic States: On the Differences between Brain In Vitro and In Vivo Conditions and Monitoring. J. of World Mitochondria Society, Issue n°1, Vol. 2 DOI : 10.18143/JWMS_v2i1.955. (241)

Additional key References

Barbiro E, Zurovsky Y, & Mayevsky A (1998). Real time monitoring of rat liver energy state during ischemia. Microvasc Res 56, 253-260.

Bolognese P, Miller JI, Heger IM, & Milhorat TH (1993). Laser-Doppler flowmetry in neurosurgery. J Neurosurg Anesthesiol 5, 151-158.

Chance B, Cohen P, Jobsis F, & Schoener B (1962). Intracellular oxidation-reduction states in vivo. Science 137, 499-508.

Cordeiro PG, Kirschner RE, Hu Q-Y, Chiao JJC, Savage H, Alfano RR, Hoffman LA, & Hidalgo DA (1995). Ultraviolet excitation fluorescence spectroscopy: A noninvasive method for the measurement of redox changes in ischemic myocutaneous flaps. Plast Reconstr Surg 96, 673-680.

Coremans JMCC, Ince C, Bruining HA, & Puppels GJ (1997). (Semi-)Quantitive Analysis of reduced Nicotinamide Adenine Dinucleotide Fluorescence images of blood-perfused rat heart. Biophys J 72, 1849-1860.

Dora E, Gyulai L, & Kovach AGB (1984). Determinants of brain activation-induced cortical NAD/NADH responses in vivo. Brain Res 299, 61-72.
Dora E & Kovach AGB (1982). Effect of acute arterial Hypo- and Hypertension on cerebrocortical NAD/NADH redox state and vascular volume. J CBF Metab 2, 209-219.

Ince C, Coremans JMCC, & Bruining HA (1992). In vivo NADH fluorescence. In Adv. Exp. Med. :Oxygen Transport to Tissue XIV, eds. Erdmann W & Bruley DF, pp. 277-296. Plenum Press, New York

Jobsis FF, O’Connor M, Vitale A, & Vreman H (1971). Intracellular redox changes in functioning cerebral cortex. I. Metabolic effects of epileptiform activity. Neurophysiology 3465, 735-749.

Johansson K (1988). Gastrointestinal application of laser Doppler flowmetry. An experimental and clinical study in cat and man. Acta Chir Scand Suppl 545, 1-64.

Koretsky AP, Katz LA, & Balaban RS (1987). Determination of pyridine nucleotide fluorescence from the perfused heart using an internal standard. Am J Physiol 253, H856-H862.

Mayevsky A (1984). Brain NADH redox state monitored in vivo by fiber optic surface fluorometry. Brain Res Rev 7, 49-68.

Mayevsky A (1993). Biochemical and physiological activities of the brain as in vivo markers of brain pathology. In Cerebral, Revscularization, eds.
Bernstein EF, Callow AD, Nicolaides AN, & Shifrin EG, pp. 51-69. Med-Orion Pub.

Mayevsky A & Chance B (1982). Intracellular Oxidation-Reduction State Measured in Situ by a Multicannel Fiber-Optic Surface Fluorometer. Science 217, 537-540.

Mayevsky A, Doron A, Manor T, Meilin S, Zarchin N, & Ouaknine GE (1996). Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res 740, 268-274.

Mayevsky A, Meilin S, Manor T, Ornstein E, Zarchin N, & Sonn J (1998). Multiparametric monitoring of brain oxygen balance under experimental and clinical conditions. Neurol Res 20, S76-S80.

Mayevsky A, Sonn J, Luger-Hamer M, & Nakache R (2003). Real time assessment of organ vitality during the transplantation procedure. Transplantation Revs 17, 96-116.

Osbakken M & Mayevsky A (1996). Multiparameter monitoring and analysis of in vivo ischemic and hypoxic heart. J Basic Clin Physiol Pharmacol 7, 97-113.

Rampil IJ, Litt L, & Mayevsky A (1992). Correlated, simultaneous, multiple-wavelength optical monitoring in vivo of localized cerebrocortical NADH and brain microvessel hemoglobin oxygen saturation. J Clin Monit 8, 216-225

Schabauer AM & Rooke TW (1994). Cutaneous laser Doppler flowmetry: applications and findings. Mayo Clin Proc 69, 564-574.

Westerman RA, Widdop RE, Hannaford J, Low A, Roberts RG, Kent P, Sideris K, Yip T, Hales JR, & Stephens FR (1988). Laser Doppler velocimetry in the measurement of neurovascular function. Australas Phys Eng Sci Med 11, 53-66.